The Best Enzyme Cleaner for Dog Urine

The Best Enzyme Cleaner for Dog Urine

When it comes to keeping our homes clean and free from unwanted pet odors and stains, one essential product that comes to mind is the pet enzyme cleaner. Whether you have a furry feline friend or a loyal canine companion, accidents can happen, and it’s crucial to have the right tool in your cleaning arsenal.

Pet enzyme cleaners are specifically designed to tackle the stubborn stains and lingering odors left behind by our beloved pets. These remarkable cleaning solutions are formulated with enzymes that break down the organic matter present in urine and other pet messes. This enzymatic action not only removes the visible stains but also eliminates the underlying source of the odor, ensuring a fresh and clean living space.

However, not all enzyme cleaners are created equal, and choosing the right one can make a world of difference in effectively cleaning up pet accidents. The key is to select a product that is tailored to your specific needs. Different stains may require different enzymes for complete removal, so it’s essential to find a cleaner that targets the particular type of mess you’re dealing with.

To assist you in your quest for the best enzyme cleaner for dog urine, I’m here to provide you with valuable insights and recommendations. Whether you’re dealing with a recent accident or a long-standing stain, finding the right enzyme cleaner can help you say goodbye to those persistent pet messes once and for all.

In the following discussion, we’ll explore various enzyme cleaner options, their unique features, and how they can effectively tackle different types of pet stains. So, let’s embark on this journey to discover the perfect solution for maintaining a clean and odor-free home despite the occasional mishaps of our beloved pets.

Top 11 Enzyme Cleaners Review – Top Pick Reviewed

Below are some of the best enzyme-based cleaners that I can recommend you get when cleaning dog urine.

1. Rocco & Roxie Supply Co Professional Strength Stain & Odor Eliminator – Small Size 

The first product I will introduce comes from Rocco & Roxie Supply Co, a brand that is known to provide quality cleaners. It is a product that removes residue, odors, and stains left behind by pets.

One thing I find to be satisfying about this product is the enzyme activated formula that gets to the root of the problem. That is all possible thanks to the natural enzymatic bacteria that feed on stains and odors.

The other feature that I love about this cleaner is the fact it is certified to be safe and gentle. It does not contain color or chlorine and won’t hurt children and pets.


  • 100% satisfaction guaranteed
  • For all surfaces
  • No hazardous product


  • Comes in a small bottle

2. Rocco & Roxie Supply Co Professional Strength Stain & Odor Eliminator – Big Size 

If you want to clean bigger surfaces or there is a lot of mess to clean, then I would recommend you get this container. The first thing I like about this cleaner is that it comes with the Seal of Approval from the Carpet and Rug Institute.

I also like the fact that it cleans odors, stains, and residue to leave the floor looking clean and smelling fresh. Besides, the model is perfect for cleaning litter boxes, clothing, rugs, carpets, all pet living areas, pet sleeping areas, and kennels.

Like the first product, this cleaner is made using an enzyme formula that gets to the root cause of the stain. I bet it feeds on urine and stains to leave a fresh surface.


  • Safe for home use
  • Easy to use
  • Has seal of approval


  • No spraying bottle

3. Out Advanced Stain and Odor Remover

I must start by stating that this product has 3x-concentration that most enzyme cleaners out there. It can quickly get rid of odor and stains, including feces, vomit, blood, urine, and more.

The other thing I should inform you about is that it prevents your dog from messing the same spot again using pheromones. And it is made of safe ingredients that cannot harm your kids or pets.

I also find it to be quite useful in cleaning almost all types of floors.


  • Discourages repeat messing
  • Remove odor and stains
  • 3x-concentration


  • A bit strong

4. Nature’s Miracle New Formula Advanced Stain & Odor Remover

I was looking for a product that can clean severe dog messes, and I can confidently say this is the right one. It can quickly get rid of tough odors and stains from dog vomit, diarrhea, and urine.

I also find it to provide a light, fresh scent that makes a home smell clean for long. And it continues to work if there is a bio-based stain on the floor.

The best thing I love about this cleaner is the ability to discourage resoling. You also don’t need to worry about your pet or kid after cleaning the floor using this cleaner.


  • Safe to use
  • Prevents repeat soiling
  • Value for money


  • Takes time to clean

5. Nature’s Miracle Laundry Boost 

Here I have a product that you might want if you want to get rid of odors and stains on your laundry. You can easily add it to your wash loads for it to work the magic and leave your clothes smelling fresh.

I find it to be quite astonishing because you can use it in both cold and hot water and it quickly brightens and whitens clothes. That is all possible due to the phosphate-free cleaning formula that breaks down messes.

It is also a cleaner that can remove oil and grease and is guaranteed to work.


  • Value for money
  • Safe for all washers
  • Use in both cold and hot water


  • Mainly for laundry

6. Clorox Urine Remover for Stains and Odors 

Another stains and odors remover that I can recommend to you is this Clorox Urine model. It breaks down urine to mask and remove smell, while its hydrogen peroxide eliminates stains.

I find it easy to use, mainly due to the spray bottle that you can hold for hours without getting fatigue. That only makes it a user-friendly product that can remove any evidence of dog or cat urine from your house.

What more, the product is safe to use on soft surfaces and fibers, which I like because it takes care of bed linens, mattresses, and others. You can also use it to disinfect nonporous surfaces like sidewalks and concrete.


  • Removes all stains
  • For soft fibers
  • Comes in a spray bottle


  • Takes time to dry

7. Nature’s Miracle Sunny Lemon Advanced Stain and Odor Eliminator

Sunny Lemon from Nature’s Miracle is a product that I especially love for its fresh smell. It boasts of powerful enzyme formula that helps to remove all tough stains and smell of dog diarrhea, urine, and vomit.

I like the fact that it continues to work even after cleaning is done – that is to remove all messes. And it comes from a reputable brand that provides high-quality products.

Another thing I find to be enjoyable with this cleaner is the ability to discourage soiling. It is a product that you should consider having at home.


  • Sunny lemon scent
  • Safe for home use
  • Discourages re-soiling


  • Not quite effective in removing stains

8. SIMPLE GREEN Outdoor Odor Eliminator 

If you want an odor remover that comes with a sprayer, then I recommend you try this model. You get a sprayer as well as the product is a huge container to allow you clean all your outdoor.

It quickly gets rid of the smell that occurs due to a dog’s vomit, stool, urine, and other organic matter. I like its versatility as you can use it for decks, yards, patios, and dog runs.

Moreover, it is made of non-toxic material that makes it safe for use in homes with pets and kids. It also boasts of a fast-acting formula that leaves your floors cleans.


  • Safe on grass
  • Removes odor
  • Comes with a sprayer


  • Doesn’t remove stains

9. Resolve Ultra Pet Stain & Odor Remover

I found this cleaner to have an effective stop technology that helps to remove pet odors within seconds. It leaves behind a fresh home with a clean scent and discourages the pet from re-soiling the floor.

You can quickly get rid of all dog stains like feces, vomit, and urine from carpets and rugs. What more, I tried it on wine, and it did a great job – it can also clean greasy food and grape juice.

The model is rated as safe for use around pets and kids. Also, it is a product that can give you value for your money.


  • Offers value for money
  • Removes all stains
  • Discourages re-soiling


  • No user instruction

10. BUBBA’S ROWDY FRIENDS Super Strength Commercial Enzyme Cleaner

BUBBA’S ROWDY FRIENDS Super Strength Enzyme Cleaner is a commercial product that I can recommend for all professional cleaners. That is because it is more potent than most cleaners in this review.

Besides, it is a product that is safe to use for upholstery, carpets, area rugs, flooring, and other places. It continues to remove stains long after cleaning is done, and it leaves a fresh scent.

You get a satisfaction guarantee from the manufacturer when you buy this product. Also, it is safe for use when cleaning bathrooms, kitchens, and other rooms in your house.


  • Professional-grade model
  • A powerful cleaner
  • For all rooms


  • Takes time to dry

11. One Fur All 100% Natural Soy Wax Candle 

Lastly, I want to give you a product that can leave your house odor-free and smell fresh. It is the One Fur Natural Soy Wax Candle.

You can use this cleaner to clean the air around your home to get rid of the dog’s urine, feces, and vomit smell. The product is made using essential oils that add to the sweet aroma it brings to a home.

And the best part is that it is friendly to people and pets and comes with 100% cotton wick. You can burn this candle for up to 60 minutes to get the high-quality air you want.


  • Removes all smell
  • Easy to use
  • Friendly to the user


  • Won’t remove stains

Choosing the Right Enzymatic Dog Cleaner

Enzyme cleaners for dog urine are made differently. Every model has different types of enzymes or a combination of these ingredients.

However, they all seem to work in the same manner to break down messes caused by pets. But there is a problem: you should get a product that contains enzymes for eliminating dog urine stain.

That also means getting a cleaner that can handle different types of messes if you have different kinds of pets. Such a product comes with multi enzymes.

With that said, there are things that you should look for to ensure that you get an effective enzyme cleaner. They include:

Product Concentration

You can get a less or more concentrated product. Ensure that you choose a more concentrated model when cleaning tough messes.

What that means is getting industrial-level cleaners – they often can with an industrial-strength label.

Smell Removing Ability 

One primary purpose of cleaning dog messes is to mask or remove the odor. The right cleaner uses enzymes and odor eliminator to remove the stain and get rid of the smell.

Don’t go for a product that covers the smell.

Stain Removing Ability 

The right cleaner should get rid of the mess first even before it acts on the smell. Such a product should remove mud, urine, feces, blood, and vomit from your floor.

Type of Delivery

These products can come in a pour bottle or a spray one. The former choice is large than the latter and gives value for the money.

You should also ensure that you buy a spray bottle to make it easier to apply the cleaner.

Pleasant Scent

It takes time for an enzyme cleaner for dog urine to work and neutralize the smell. Thus, you should choose a product that comes with a sweet aroma to mask the odor.

Application Time 

A cleaner can take up to 60 minutes before it starts to remove the stain. That will depend on what it is made of and the toughness of the mess.

Choose a cleaner that begins to work within 10 minutes.

Drying Time 

Some of the top enzyme cleaner for pet urine takes up to 12 hours before they can get off your floor. Although some can take longer, it is essential to allow the area to dry before you step on it.

A prolonged drying time gives the enzymes enough time to clean all the messes.

Gentle Product

It is especially critical when you are working with things such as carpet, bedding, and furniture. A mild cleaner won’t discolor your items.

Chemical-Free and Natural 

Since these cleaners are used in areas with pets, they must be safe both for humans and dogs. They shouldn’t contain any chemicals.

Multi-Purpose Use

From hard floor cleaning to washing cloth, you should aim to use just a single model of enzyme cleaner.

Final Verdict

After thorough examination and analysis, I have meticulously assessed the top enzyme cleaners designed specifically for tackling dog urine stains currently available in the market. Furthermore, I have crafted an informative and comprehensive buying guide to assist you in making an informed choice when selecting the perfect solution to address your unique needs.

Wise Reviewer

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